Top 7 Rookies In Week 4 2025 That Could Reshape Fantasy Lineups Today

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By: Jessica Morrison

Excitement around 7 rookies this week. These newcomers arrive at a moment when injuries and role changes are already reshaping depth charts and fantasy value. Multiple outlets flagged the same names – from a returning wideout expecting to play to fresh RB workload questions – so this list collects the clearest Week 4 bets for roster managers. Which rookie will vault into your starting lineup this weekend?

Why These seven rookies Could Change Week 4 Outcomes (Week 4, 2025)

  • Tetairoa McMillan expects to play Week 4 after a calf issue; big target upside.
  • Emeka Egbuka has sustained a high target share through three weeks; consistent role.
  • Ashton Jeanty appears in NYT rookie RB debate; workload could rise this week.

The 7 rookies reshaping fantasy lineups this week

1 – Tetairoa McMillan: returns from a calf scare with WR1 upside

Tetairoa McMillan said he expects to play Week 4 after missing practice for a calf issue, and coaches kept him in the plan. If he’s active, McMillan’s target volume makes him a lineup candidate rather than a bench stash-start him in single-digit leagues. Have you got him on your waiver wire yet?

2 – Emeka Egbuka: steady role, sneaky weekly floor for PPR managers

Emeka Egbuka continues to command looks and routes in his team’s passing attack, translating to steady PPR floor and occasional ceiling. If you need a WR who can rescue weak spots, Egbuka is worth flex consideration this week.

3 – Matthew Golden: a matchup-ready slot target with explosive plays

Matthew Golden has flashed as a high-IQ slot receiver, and matchup conditions in Week 4 look favorable for quick completions and YAC. If you like high floor plays that threaten big plays, Golden is a compelling low-risk start.

4 – Jaydon Blue: rookie RB debut could upend depth charts

Jaydon Blue’s expected debut this weekend matters because injuries have opened immediate snaps; Blue could steal passing-down work early. Consider him for deeper lineups or next-day pickups if he posts an early workload.

5 – Ashton Jeanty: the RB workload puzzle that could pay off

Ashton Jeanty sits amid a rookie RB rotation debate highlighted by the NYT; a snap-share bump this week would make him a sudden-start candidate. If you need RB help, Jeanty’s upside is tied directly to touches-monitor snap counts early.

6 – Cam Skattebo: fantasy’s surprising rookie QB/WR conversation

Cam Skattebo popped into fantasy talk as an unexpected rookie force, thanks to target volume and red-zone looks in recent weeks. If your opponent underestimates rookies, Skattebo could be the differential that wins a head-to-head matchup.

7 – Tyler Warren: tight end breakout potential on short notice

Tyler Warren’s usage profile shows increasing routes and red-zone presence, making him a TE-streaming option with upside this Week 4. If your tight end spot is thin, Warren is a matchup-aware play.

The key figures that show why these rookies matter in Week 4

Metric Value + Unit Change/Impact
Rookies highlighted in Week 4 previews 7 players More rookie chatter than Week 3
Rookie running backs discussed by NYT 3 players Intensifies RB workload uncertainty
First-round rookies graded by PFF 32 players Full grades available after early games

Rookie mentions and grades are spiking, raising immediate fantasy consequences.

How Will These 7 Rookies Reshape Your Lineups This Week?

Expect one or two of these rookies to swing fantasy outcomes; bold managers will win. Will you bench a veteran for a rookie this week?

Sources

  • https://www.espn.com/fantasy/football/story/_/id/46365618/nfl-fantasy-football-rankings-predictions-surprises-week-4
  • https://www.si.com/onsi/fantasy/dfs/matthew-golden-and-2-more-rookies-to-watch-out-for-on-sunday-night-football
  • https://www.nytimes.com/athletic/6655852/2025/09/23/rookie-running-back-questions-ashton-jeanty-fantasy-scoop-city/

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